As I mentioned earlier, I'm making an attempt to catch up on some of the great games I missed during the current generation. My list is below, but it feels incomplete. If anyone has any more suggestions, leave them in the comments. (Even if I've played your choice, we can still talk about how awesome it was. Unless you choose something terrible, in which I case I will berate you without mercy.)
Metal Gear Solid 3
Actually, although I never played Super Mario Sunshine or Wind Waker, I'm pretty sure there's nothing else I need to play on the 'Cube. Resident Evil 4 was the alpha and the omega. Prove me wrong, kids -- prove me wrong!